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Australia has defended the independence of the top international court after it issued arrest warrants for Israel's prime minister, former defence minister and a Hamas commander. The International Criminal Court (ICC) found there were reasonable grounds that Prime Minister Benjamin Netanyahu and former defence minister Yoav Gallant bore criminal responsibility for alleged war crimes. This includes allegations of using starvation as a method of warfare and directing attacks against civilians in Gaza. The warrants are not a finding of guilt. The ICC rejected Israel's challenge that it didn't have jurisdiction over the matter. Australia respects the independence of the ICC and its "important role in upholding international law", Foreign Minister Penny Wong said. "We have been clear that all parties to the conflict must comply with international humanitarian law," she said in a statement on X. Senator Wong reiterated calls for civilians to be protected, hostages to be released, aid workers to be protected and for more humanitarian aid to flow. Nationals senator Bridget McKenzie said it was troubling that the court had targeted "an elected member of a democracy, of a sovereign nation-state, trying to protect his country from terrorists". The ICC ruled it had jurisdiction to investigate the situation in Palestinian territories and that states couldn't challenge the jurisdiction prior to a warrant being issued, "thus Israel's challenge is premature". Senior coalition figures have repudiated the court's argument it has jurisdiction, arguing Australia's position should be in line with the United States, which rejected the ruling. "They're supposed to be working with nation states and their legal systems, not seeking to supplant them," Senator McKenzie said of the ICC. "We would be looking to obviously stand with the United States on this issue." However, the US isn't an ICC member state - while Australia is - and Washington previously welcomed a warrant issued against Russian President Vladimir Putin for atrocities in Ukraine. Canada Prime Minister Justin Trudeau and the European Commission foreign affairs representative Josep Borrell said they would comply with the ruling. An arrest warrant was also issued for Hamas' military wing commander Mohammed Diab Ibrahim Al-Masri for the crimes against humanity of murder, extermination, torture, and rape and other forms of sexual violence. There were reasonable grounds to believe he was also responsible for the war crimes of murder, cruel treatment, torture, taking hostages, outrages upon personal dignity, and rape and other forms of sexual violence, the court found. The decision by the independent court showed international humanitarian law needed to be upheld through fair and impartial judicial processes in all circumstances, ICC prosecutor Karim Khan said. "Our collective mind and focus should be on the victims of international crimes in Israel and in the State of Palestine," he said in a statement after the warrants were issued. Arrest warrants for the leader of Hamas in Gaza and the former head of its political bureau were withdrawn following confirmation of their deaths. The official death toll in Gaza has eclipsed 44,000, according to the local health ministry, with tens of thousands more missing or believed to be buried under rubble. Israel's war in Gaza was sparked by listed terror group Hamas' attack on October 7, 2023 that killed 1200 people and resulted in 250 hostages being taken, according to Israel's tallies. Almost 100 hostages are still missing, with 35 believed to be dead.TCMD stock touches 52-week high at $16.96 amid robust growth
Canada’s market offers a wealth of opportunities with its strong financial backbone, resource-driven energy sector, and burgeoning technology landscape. Each sector has its unique charm, and diving into them reveals promising investments that cater to different styles of investors. Let’s take a closer look at some standouts that have been grabbing attention recently. Royal Bank The financial sector remains a cornerstone of Canada’s economy, with its banks standing tall on the global stage. Among them, ( ) continues to solidify its position as a leader. Recently, RBC reported an impressive 17.7% jump in adjusted net income for the quarter, reaching a remarkable $4.44 billion. This was fuelled in part by its acquisition of HSBC’s Canadian operations, a strategic move that has brought in nearly 780,000 new clients and significantly bolstered its retail and commercial banking services. Add to this a strong performance in wealth management, where rising fees and improved market conditions have helped drive growth, and RBC stands out as a compelling choice for those seeking steady, long-term returns. Even as it prudently sets aside funds for potential loan defaults, its strong fundamentals and strategic vision point to a bright future. Enbridge Turning to the energy sector, ( ) remains a powerhouse, particularly in a country rich in natural resources. The Canadian stock’s recent guidance for 2025 has caught the attention of many, projecting adjusted core earnings of up to $20 billion. Such confidence is backed by its strategic expansion efforts, including the acquisition of three utilities from Dominion Energy for $14 billion. This deal solidified Enbridge’s position in the gas distribution business, complementing its extensive operations. Plans to invest nearly $7 billion in 2025 underline its growth ambitions, while a 3% dividend increase demonstrates its commitment to rewarding shareholders. With energy demand remaining robust and Enbridge’s ability to innovate and adapt, it’s clear this Canadian stock is poised to deliver both value and growth. Shopify In the technology space, ( ) continues to shine as one of Canada’s most exciting growth stories. As the largest tech company in the country by market capitalization, Shopify has transformed the e-commerce landscape, enabling businesses of all sizes to thrive online. Its platform is now utilized by more than 26,000 customers in over 160 countries, showcasing its global appeal and scalability. Shopify’s journey has been nothing short of remarkable, with exponential growth during the pandemic cementing its status as a leader in tech innovation. While recent earnings specifics may be missing, the Canadian stock’s forward momentum is unmistakable. Shopify’s ability to continually evolve its platform and meet the needs of a dynamic market makes it a standout, especially for investors seeking high-growth potential. Foolish takeaway Investing in Canada isn’t just about finding companies that perform well in the short term. It’s about tapping into a diversified economy that balances with innovation. RBC, Enbridge, and Shopify all highlight how different sectors can cater to various investor needs, whether it’s steady income, capital appreciation, or explosive growth. As the world looks for economic stability, Canada stands out as a safe haven for investment. There’s something here for everyone. Whether you’re drawn to the security of banking, the tangible assets of energy, or the dynamism of technology. RBC, Enbridge, and Shopify exemplify the best that Canada has to offer—each carving out its place in a market full of potential. As always, a thoughtful approach to research and alignment with personal financial goals will help ensure that investments pay off, not just in dollars but in peace of mind.The Israeli Justice Ministry made the announcement in a message late on Thursday, saying the investigation would focus on the findings of a recent report by the Uvda investigative programme into Sara Netanyahu. The programme uncovered a trove of WhatsApp messages in which Mrs Netanyahu appears to instruct a former aide to organise protests against political opponents and to intimidate Hadas Klein, a key witness in the trial. The announcement did not mention Mrs Netanyahu by name and the Justice Ministry declined further comment. Earlier on Thursday, Mr Netanyahu blasted the Uvda report as “lies”. It is the latest in a long line of legal troubles for the Netanyahus, highlighted by the PM’s ongoing corruption trial. Mr Netanyahu is charged with fraud, breach of trust and accepting bribes in a series of cases alleging he exchanged favours with powerful media moguls and wealthy associates. He denies the charges and says he is the victim of a “witch hunt” by overzealous prosecutors, police and the media.As the Canada Postal worker strike drags on into a third week, the Canadian Federation of Independent Business (CFIB) is calling on the federal government to step in. "Seventy-five per cent of small businesses in Canada are impacted by the strike at Canada Post, and it's costing small businesses a huge amount of money; $76 million per day is lost because of the strike," said Jasmin Guenette, CFIB National Affairs Vice-President. "If the strike doesn't end by Wednesday, it will have cost small businesses $1 billion in revenue." According to the CFIB, that includes a combination of lost sales and the increased cost of doing business. It's a busy time of year for local businesses, which have had to pivot, including Vamos Outdoors in Almonte. "We are very blessed, we have wonderful customers," said owner Lisa Nye-Labonte. "November and December are our busiest months of the year." Nye-Labonte says the business increased the price of shipping by 10 per cent to adjust to other carriers like UPS and it has hit pause on overseas sales. "Internationally, we have noticed the price is quite high and so, in those instances, we have refunded orders and lost sales due to that," she said. The CFIB says it's small businesses who are paying the price. "Either impose binding arbitration or introduce back-to-work legislation because the strike cannot continue for many more days," said Guenette. The United States Postal Service has also suspended mail and package delivery to Canada temporarily. This comes as some local businesses like Needle in a Craft Stack close online stores temporarily. "Eighty per cent of my shop is letter mail, so a couple postal stamps compared to shipping to someone's front door is a huge jump," said owner Melissa Tachie-Menson. As the strike continues into the busiest time of year, it begs the question of whether businesses like Vamos Outdoors will return once it's over. "I don't know," said Nye-Labonte. "It is convenient for us, but I do feel that they do need to make some changes." Canada Post says it presented the union with a framework to reach negotiated agreements in the dispute, while the union says its negotiators are reviewing the proposal. Shopping Trends The Shopping Trends team is independent of the journalists at CTV News. We may earn a commission when you use our links to shop. Read about us. Editor's Picks The Ultimate 2024 Holiday Gift Guide For People Who Love Working Out 22 Gifts That Are Guaranteed To Impress Just About Anyone All The Best Beauty Stocking Stuffers That Ring In Under $25 Home Our Guide To The Best Hydroponic Gardens In Canada In 2024 (And Where To Get Them) Our Guide To The Best Cookware Sets In Canada In 2024 (And Where To Get Them) Our Guide To The Best Space Heaters In Canada In 2024 (And Where To Get Them) Gifts 15 Gifts That'll Pry Their Eyes Away From Screens For A Bit 20 Brilliant Gift Ideas Under $75 21 Of The Best Gift Ideas For Women Under $300 Beauty Our Guide To The Best Self Tanners You Can Get In Canada 20 Anti-Aging Skincare Products That Reviewers Can’t Stop Talking About 12 Budget-Friendly Makeup Brushes And Tools Worth Adding To Your Kit Deals The Waterpik Advanced Water Flosser Will Make Cleaning Your Teeth So Much Easier — And It's 40% Off For Cyber Monday Here Are All The Best Amazon Cyber Monday Deals You Can Find On Beauty Products In Canada Here Are All The Best Amazon Cyber Monday Deals You Can Find On Stocking Stuffers In Canada Ottawa Top Stories Kingston, Ont. doctor in 'disbelief' after being ordered to repay $600K for pandemic vaccination payments Multiple elements contributed to fatal Chinook helicopter crash in Ottawa River, investigation concludes City of Ottawa's auditor general finds kickback scheme involving city employee and local landlords CFIB calls on government to step in and end postal worker strike as small business losses mount Ottawa shoppers head to the malls for Cyber Monday deals Watertown, N.Y. residents react to first lake-effect snowfall of the season leaving 90 cm behind Salvation Army workers at Ottawa shelter vote in favour of strike Ottawa police seek missing 67-year-old man CTVNews.ca Top Stories Alberta RCMP officer charged with 2 counts of sexual assault Const. Bridget Morla, a Leduc RCMP officer, has been charged with two counts of sexual assault in connection with an incident that happened two years ago. Ontario dad removes hockey rink at heart of neighbour dispute A Markham dad who drew the ire of neighbours and the city after installing a hockey rink in his backyard says the rink has now been taken down. Motivated by obsession: Canadians accused in botched California murder plot in police custody Two Canadians are in police custody in Monterey County, California, after a triple stabbing police say was motivated by a B.C. man's obsession with a woman he played video games with online. Kingston, Ont. doctor in 'disbelief' after being ordered to repay $600K for pandemic vaccination payments An Ontario health tribunal has ordered a Kingston, Ont. doctor to repay over $600,000 to the Ontario government for improperly billing thousands of COVID-19 vaccinations at the height of the pandemic. Trump demands immediate release of Oct. 7 hostages, says otherwise there will be 'HELL TO PAY' President-elect Donald Trump is demanding the immediate release of the Israeli hostages still being held in Gaza, saying that if they are not freed before he is sworn into office there will be “HELL TO PAY." Alleged gang member driving from U.S. arrested at Canadian border after making wrong turn An alleged gang member coming from the United States was arrested at the Canadian border after reportedly making a wrong turn onto the Peace Bridge border crossing. AC/DC announces North American stadium tour, Vancouver lone Canadian stop Big news for AC/DC fans as the heavy metal bigwigs announced Monday they will hit the road next spring. But as of now, there’s only one Canadian show on the docket. Nova Scotia lawyer suspended following ugly courtroom fracas A Nova Scotia lawyer who had to be restrained by deputy sheriffs during a court appearance earlier this year has lost his appeal of a suspension following the bizarre incident. Negotiations between Canada Post, union still on hold Canada Post says it's waiting for a response from the union representing some 55,000 striking workers after it offered a new framework for negotiations over the weekend. Atlantic Nova Scotia lawyer suspended following ugly courtroom fracas A Nova Scotia lawyer who had to be restrained by deputy sheriffs during a court appearance earlier this year has lost his appeal of a suspension following the bizarre incident. Woman dies after side-by-side crash in Belnan, N.S. A 22-year-old woman has died following a collision between a side-by-side and a vehicle in Belnan, N.S., over the weekend. Man dead, another injured after suspicious New Brunswick house fire One man is dead and a second is badly injured after a suspicious house fire in Coal Creek, N.B. Toronto Toronto library apologizes after staff at east-end branch refuse to help lost girl The Toronto Public Library is apologizing after staff at a branch in the city’s east end refused to provide a lost child with access to a telephone. Metrolinx CEO Phil Verster tenders resignation after 7 years Metrolinx CEO Phil Verster is stepping down. Verster tendered his resignation on Monday in order to take a new position and will leave his role as CEO of the provincial transit agency as early as Dec. 16. Crews partially reopen highway north of Toronto after major snowstorm hits cottage country Crews have partially reopened Highway 11 north of Toronto this afternoon after parts of Ontario’s cottage country were hit with upwards of 140 centimetres of snowfall over the weekend. Montreal New poll suggests Legault even less popular than Justin Trudeau A prominent polling analyst says Quebec's governing party would be reduced to fewer than 10 seats in the provincial legislature if an election were held today, based on current poll numbers. Montreal's Metro will have extended service hours on New Year’s Eve To help Montrealers celebrate the holidays safely, the Metro will run later than usual on New Year’s Eve. Lightspeed Commerce cutting 200 jobs as it eyes profitable growth Northern Ontario Five years after toddler's brutal death, Northern Ont. family struggles to find peace, justice A North Bay family is struggling to find peace and justice as the five-year anniversary of the brutal death of toddler Oliver McCarthy approaches. Transport trucks collide head-on near Hearst, Ont. One transport truck driver was seriously injured Saturday when two commercial motor vehicles collided head-on on Highway 11 Northwestern Ontario community fined for refusing to celebrate Pride Month An Ontario town and its mayor have been fined a total of $15,000 for refusing to celebrate Pride Month. Windsor 'We don’t give up on people': Windsor mobile soup kitchen moving indoors A mobile soup kitchen in downtown Windsor is moving indoors. 51-year-old woman faces impaired driving charge after veering into traffic: WPS Windsor police charged a 51-year-old woman with impaired driving after she allegedly veered into oncoming traffic, causing a crash in east Windsor. Crash investigation leads to impaired driving charges Elgin OPP officers have charged a Chatham driver following a collision investigation. London 'It's painful to see that': Neighbours express concern for children impacted by Sarnia homicide investigation Just before 5 a.m. on Sunday, police were called to a rooming house 194 Queen St. where two residents were involved in a physical fight while in the kitchen. Startling admission by defence at bush bash shooting trial As the lengthy bush bash shooting trial resumed this week, the day started with a stunning admission from defence lawyer Ricardo Golec, who represents the accused in this case, 23-year-old Carlos Guerra Guerra. 'Snow streamer' moves across the region with snow squall warning still in effect A snowsquall warning is in effect for southern Ontario with more snow on the way. Kitchener Experts surprised by rising number of walking pneumonia cases Experts say a rise in respiratory illness is expected as the temperature drops, but this year, they’re seeing a surprising number of walking pneumonia cases in younger people. A Better Tent City community mourns the loss of a resident killed in shooting People living at a tiny home project in Kitchener are mourning the loss of one of their own. Crews partially reopen highway north of Toronto after major snowstorm hits cottage country Crews have partially reopened Highway 11 north of Toronto this afternoon after parts of Ontario’s cottage country were hit with upwards of 140 centimetres of snowfall over the weekend. Barrie Health experts provide safety tips amid Gravenhurst State of Emergency Health officials urge residents to take extra precautions following the State of Emergency declared in Gravenhurst. New bridge over Highway 400 in Barrie opens to traffic The Sunnidale Road bridge replacement is complete, with the road opening to traffic Monday. 4 arrested in cocaine bust during R.I.D.E. spot check: OPP Five people were arrested in a single vehicle at a R.I.D.E. check. Winnipeg Material at Manitoba landfill now being searched for remains of Indigenous women The next stage in the search for the remains of two slain Indigenous women in a Manitoba landfill has officially begun. Two people found dead at Portage la Prairie home: RCMP The Manitoba RCMP is investigating after two people were found dead at a home in Portage la Prairie over the weekend. Northwestern Ontario community fined for refusing to celebrate Pride Month An Ontario town and its mayor have been fined a total of $15,000 for refusing to celebrate Pride Month. Calgary Apartment in downtown Calgary highrise significantly damaged in fire Calgary fire crews are investigating a blaze that significantly damaged an apartment in a downtown highrise on Monday morning. Silverado residents concerned with proposed cellphone tower Some long-time residents in Calgary's deep southwest neighborhood of Silverado are pushing back against a proposed cellphone tower. Calgary's 5 most expensive homes for sale right now Calgary's most expensive homes as of December 2024. Edmonton Alberta RCMP officer charged with 2 counts of sexual assault Const. Bridget Morla, a Leduc RCMP officer, has been charged with two counts of sexual assault in connection with an incident that happened two years ago. Alberta reannounces plans to reduce number of photo radar sites Alberta reannounced plans to reduce photo radar sites in the province on Monday. VIDEO | Northern Alta. house explosion likely caused by gas leak: RCMP Northern Alberta Mounties are investigating a house explosion in Swan Hills early Monday morning. Regina Manz found guilty of one charge of sexual assault, acquitted on five others after 57 hours of deliberations After being sequestered for more than 57 hours, a 12-person jury has found Regina chiropractor Ruben Manz guilty of one count of sexual assault. Blockbuster WHL trade sees Warriors move captain Brayden Yager to Hurricanes The Western Hockey League's (WHL) Moose Jaw Warriors traded captain Brayden Yager to the Lethbridge Hurricanes Monday. Over 7,000 Sask. patients have intimate medical info breached in lab hack Over 7,000 patients in Saskatchewan had their intimate medical information breached by hackers, according to the province’s privacy watchdog. Saskatoon Over 7,000 Sask. patients have intimate medical info breached in lab hack Over 7,000 patients in Saskatchewan had their intimate medical information breached by hackers, according to the province’s privacy watchdog. Family of Sask. man who died following a violent arrest still pushing for answers Friends and family of Boden Umpherville may be closer to finding answers on the circumstances surrounding his death. 'The best start': Saskatoon begins 2025 budget talks with proposed cut to property taxes In an unusual twist, the latest City of Saskatoon budget deliberations began with positive financial news. Vancouver Driver 'doing donuts' crashes into house in Nanaimo, B.C.: RCMP A driver who was “doing donuts” in a roundabout on a residential street in Nanaimo, B.C., lost control of his car and crashed into a home, according to police. Knife-wielding man arrested following incident in Richmond, B.C. A man who allegedly threatened the public with a weapon and chased a woman in Richmond, B.C., has been arrested. ‘A piece of our hearts missing:’ B.C. family announces tragic end to search for missing man with dementia A 64-year-old man who went missing from his Saanich long-term care home last month has been found deceased on the Westshore – with his wallet and Cleveland Browns trading cards, according to family. Vancouver Island Driver 'doing donuts' crashes into house in Nanaimo, B.C.: RCMP A driver who was “doing donuts” in a roundabout on a residential street in Nanaimo, B.C., lost control of his car and crashed into a home, according to police. ‘A piece of our hearts missing:’ B.C. family announces tragic end to search for missing man with dementia A 64-year-old man who went missing from his Saanich long-term care home last month has been found deceased on the Westshore – with his wallet and Cleveland Browns trading cards, according to family. Fraudulent B.C. crypto platform fined $18.4M by securities regulator The British Columbia Securities Commission has fined a cryptocurrency trading platform and its director more than $18 million after finding the company lied to its customers by diverting nearly $13 million of their investments into gambling websites and personal accounts. Kelowna Study of 2023 Okanagan wildfires recommends limiting development in high-risk areas A study into the devastating wildfires that struck British Columbia's Okanagan region in 2023 has recommended that government and industry limit development in high-fire-risk areas. Kelowna, B.C., to host the Memorial Cup in the spring of 2026 The Western Hockey League's Kelowna Rockets will host the Memorial Cup in the spring of 2026, the Canadian Hockey League said Wednesday. 545 vehicles impounded in 332 days: BC Highway Patrol pleads for drivers to slow down Mounties with the BC Highway Patrol in Kelowna say they've impounded more than 545 vehicles for excessive speed and aggressive driving so far this year. That works out to more than 1.6 per day. Stay Connected
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Decision follows observations of liver transaminitis without clinically significant symptoms in some subjects on azelaprag Company will evaluate data from patients enrolled to date and share updated plans for azelaprag in Q1 2025 In parallel to evaluating azelaprag, Company will continue to advance earlier platform-derived programs, including IND submission for CNS penetrant NLRP3 inhibitor anticipated in the second half of 2025 RICHMOND, Calif., Dec. 06, 2024 (GLOBE NEWSWIRE) -- BioAge Labs (Nasdaq: BIOA) (“BioAge”, “the Company”), a clinical-stage biopharmaceutical company developing therapeutic product candidates for metabolic diseases by targeting the biology of human aging, today announced that the Company has made the decision to discontinue the ongoing STRIDES Phase 2 study of its investigational drug candidate azelaprag as monotherapy and in combination with tirzepatide after liver transaminitis without clinically significant symptoms was observed in some subjects receiving azelaprag. No transaminase elevations were observed in the tirzepatide only treatment group. “Patient safety is our top priority in the conduct of our clinical studies,” said Kristen Fortney, PhD, CEO and co-founder of BioAge. “We made the difficult decision to discontinue the STRIDES Phase 2 study of azelaprag because it became clear that the emerging safety profile of the current doses tested is not consistent with our goal of a best-in-class oral obesity therapy. While this outcome is a significant disappointment, we remain encouraged by azelaprag’s promising preclinical and Ph1b efficacy profile. We remain committed to our focus on developing therapies for metabolic aging. In parallel to assessing the next steps for the azelaprag program, we will continue to advance our NLRP3 inhibitor program as well as additional research programs with novel mechanisms emerging from our platform.” STRIDES is a randomized, double-blind, placebo-controlled Phase 2 clinical trial of azelaprag as monotherapy and in combination with tirzepatide that planned to enroll approximately 220 individuals with obesity aged 55 years and older ( link ). The trial was designed to evaluate the efficacy as measured by body weight reduction and other outcomes, safety, and tolerability of two oral doses of azelaprag (300 mg, once or twice daily) in combination with tirzepatide (5 mg subcutaneous injection once weekly). An azelaprag monotherapy arm was included to provide additional safety information. Of 204 subjects enrolled in STRIDES as of today, 11 subjects in the azelaprag treatment groups were observed to have transaminase elevations with no clinically significant symptoms. Dosing of all subjects will be discontinued, and no additional subjects will be enrolled. Clinical follow-up of enrolled subjects will continue off drug. The Company intends to further analyze available STRIDES clinical data from all enrolled subjects. The Company has notified all study investigators and regulatory authorities including the U.S. Food and Drug Administration (FDA) of the Company’s decision to discontinue enrollment. The Company intends to share updated plans for azelaprag in Q1 2025. BioAge continues to advance its pipeline of therapeutic candidates targeting the biology of aging to treat metabolic diseases. The Company's novel class of brain-penetrant NLRP3 inhibitors, which have demonstrated high potency and a novel binding site, are progressing toward IND submission, anticipated in the second half of 2025. The NLRP3 inhibitor program targets neuroinflammation, which is linked to both metabolic and neurodegenerative diseases. In addition, BioAge is advancing multiple targets derived from its proprietary discovery platform, which analyzes molecular data spanning over 50 years of human aging trajectories. About BioAge Labs, Inc. BioAge is a clinical-stage biopharmaceutical company developing therapeutic product candidates for metabolic diseases, such as obesity, by targeting the biology of human aging. BioAge’s lead product candidate, azelaprag, is an orally available small molecule agonist of APJ that was observed to promote metabolism and prevent muscle atrophy on bed rest in a Phase 1b clinical trial. BioAge is also developing orally available small molecule brain penetrant NLRP3 inhibitors for the treatment of diseases driven by neuroinflammation. BioAge’s preclinical programs, based on novel insights from the company’s discovery platform built on human longevity data, address key pathways in metabolic aging. Forward-looking statements This press release contains “forward-looking statements” within the meaning of, and made pursuant to the safe harbor provisions of, the Private Securities Litigation Reform Act of 1995. All statements contained in this press release that do not relate to matters of historical fact should be considered forward-looking statements, including, but not limited to, statements regarding our plans to develop and commercialize our product candidates, our business strategy, results of our ongoing or planned clinical trials, the timing of any future updates to our programs and the clinical utility of our product candidates. These forward-looking statements may be accompanied by such words as “aim,” “anticipate,” “believe,” “could,” “estimate,” “expect,” “forecast,” “goal,” “intend,” “may,” “might,” “plan,” “potential,” “possible,” “will,” “would,” and other words and terms of similar meaning. These statements involve risks and uncertainties that could cause actual results to differ materially from those reflected in such statements, including: our ability to develop, obtain regulatory approval for and commercialize our product candidates; the timing and results of preclinical studies and clinical trials; the risk that positive results in a preclinical study or clinical trial may not be replicated in subsequent trials or success in early stage clinical trials may not be predictive of results in later stage clinical trials; risks associated with clinical trials, including our ability to adequately manage clinical activities, unexpected concerns that may arise from additional data or analysis obtained during clinical trials, regulatory authorities may require additional information or further studies, or may fail to approve or may delay approval of our drug candidates; the occurrence of adverse safety events; failure to protect and enforce our intellectual property, and other proprietary rights; failure to successfully execute or realize the anticipated benefits of our strategic and growth initiatives; risks relating to technology failures or breaches; our dependence on collaborators and other third parties for the development of product candidates and other aspects of our business, which are outside of our full control; risks associated with current and potential delays, work stoppages, or supply chain disruptions; risks associated with current and potential future healthcare reforms; risks relating to attracting and retaining key personnel; failure to comply with legal and regulatory requirements; risks relating to access to capital and credit markets; and the other risks and uncertainties that are detailed under the heading “Risk Factors” included in BioAge’s Form 10-Q filed with the U.S. Securities and Exchange Commission (SEC) on November 7, 2024, and other filings with the SEC filed from time to time. BioAge undertakes no obligation to publicly update any forward-looking statement, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise. Contacts PR: Chris Patil, media@bioagelabs.com IR: Elena Liapounova, ir@bioagelabs.com Partnering: partnering@bioagelabs.com Web: https://bioagelabs.com
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